Reported Adverse Event Cases of Methemoglobinemia Associated With Benzocaine Products
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چکیده
منابع مشابه
Reported adverse event cases of methemoglobinemia associated with benzocaine products.
BACKGROUND Methemoglobinemia (MHb) is characterized by abnormal levels of oxidized hemoglobin that cannot bind and transport oxygen. When induced by benzocaine anesthetic spray and other chemicals, it can result in cyanosis and life-threatening complications. METHODS From 818 439 adverse event reports received by the US Food and Drug Administration from November 1997 through March 2002, we ex...
متن کاملBenzocaine-induced methemoglobinemia.
A case is reported in which a patient developed methemoglobinemia-induced cyanosis while under general anesthesia during surgery for multiple fascial space infections. The cause of methemoglobinemia was 20% benzocaine spray used for local anesthesia before intubation. Acutely developing methemoglobinemia is infrequently encountered in clinical practice. When confronted with cyanosis in the abse...
متن کاملBenzocaine-Induced Methemoglobinemia: A Case Report.
Topical anesthetics, such as benzocaine, have been reported to cause methemoglobinemia, in which hemoglobin is unable to release oxygen effectively to body tissues. The pathophysiology, symptoms, and treatment of a 46-year-old patient are examined.
متن کاملAcute Methemoglobinemia Secondary to Topical Benzocaine Spray
CASE REPORT An 82-year-old white woman with a history of hypertension, paroxysmal atrial tachycardia, and hypothyroidism underwent laparoscopic left adrenalectomy for possible adrenal carcinoma. On the third postoperative day, the patient’s course was complicated by a paralytic ileus. A nasogastric tube was placed, preceded by a 3-second dose of Hurricane spray (20% benzocaine, approximately 60...
متن کاملBenzocaine-induced methemoglobinemia during transesophageal echocardiography.
Acquired or toxic methemoglobinemia is an uncommon complication of topically administered anesthetic agents in patients of all ages-but particularly in pediatric and elderly patients. This report describes a case of acquired methemoglobinemia that occurred after benzocaine spray was applied orally to a 69-year-old white woman weighing 175 lb who was undergoing transesophageal echocardiography. ...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 2004
ISSN: 0003-9926
DOI: 10.1001/archinte.164.11.1192